Moens, L., Boon, L. et al Infection and Immunity 2007, 75: 5748–5752
Specific intracellular adhesion molecule-grabbing non-integrin R1 is not involved in the murine antibody response to Pneumococcal polysaccharides.
Li, S., Boon, L. et al Blood 2007, 110: 3926-3935
Rapidly induced, T-cell-independent xenoantibody production is mediated by marginal zone B cells and require help from NK cells.
Smit, J.J.,Boon, L. et al American Journal of Pathology 2007, 171: 1-8
Virus-induced regulation of asthma-like responses in mice depends upon CD8 T-cells and interferon-γ production.
Luce, A. de, Boon, L. et al Journal of Immunology 2007, 179: 5999-6008
Functional yet balanced reactivity to Candida albicans requires TRIF, MyD88, and IDO-dependent inhibition of Rorc.
Moens, L., Boon, L. et al Journal of Leukocyte Biology 2007, 82: 1-7
Distinct approaches to investigate the importance of the murine 4-1BB–4-1BBL interaction in the antibody response to Streptococcus pneumoniae.
Geboes, L., Boon, L. et al Arthritis & Rheumatism 2007, 56: 2595-2607
Freund’s Complete Adjuvant induces arthritis in mice lacking a functional Interferon-γ receptor by triggering Tumor Necrosis Factor α-driven osteoclastogenesis.
Fevery, S., Boon, L. et al Leukemia 2007, 21: 1451-1459
CTLA-4 blockade in murine bone marrow chimeras induces a host-derived anti-leukemic effect without graft-versus-host disease.
Wijk, F. van, Boon, L. et al Journal of Immunology 2007, 178: 6894-6900
The CD28/CTLA-4-B7 Signaling Pathway Is Involved in Both Allergic Sensitization and Tolerance Induction to Orally Administered Peanut Proteins.
Grauer, O.M., Boon, L. et al International Journal Cancer 2007, 121: 95-105
CD4 1 FoxP3 1 regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo.
Wijk, F. van, Boon, L. et al Clinical & Experimental Allergy 2007, 37: 572–581
CD4+ CD25+ T cells regulate the intensity of hypersensitivity responses to peanut, but are not decisive in the induction of oral sensitization.
Aerts, J.M., Boon, L. et al Diabetes 2007, 56: 1341-1349
Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity.
Gaullier, J.-M., Boon, L. et al British Journal of Nutrition 2007, 97: 550-560
Six months supplementation with conjugated linoleic acid induces regional-specific fat mass decreases in overweight and obese.
Grohmann, U., Boon, L. et al Nature medicine 2007, 13: 579-586
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy.
Langeveld, M., Simons, P.J. et al Metabiolism clinical & experimental 2007, 56: 314-319
Very low serum adiponectin levels in patients with type I Gaucher disease without overt hyperglycemia.
Simons, P.J., Boon, L. et al Journal of Endocrinology 2007, 192: 289-299
Pro-inflammatory delipidizing cytokines reduce adiponectin secretion from human adipocytes without affecting adiponectin oligomerization.
Coenen, J.J.A., Boon, L. et al Bone marrow transplantation 2007, 39: 537-545
Rapamycin, not cyclosporine, permits thymic generation and peripheral preservation of CD4+ CD25+ FoxP3+ T cells.
Chen, C., Boon, L. et al Clinical Immunology 2007, 122: 53-61
Immunosuppresive activity of a pteridine derivative (4AZA1378) alleviates TNBS-induced colitis in mice.
Anti-inflammatory activity of a pteridine derivative (4AZA2096) alleviates TNBS-induced colitis in mice.
Neerven, R.J.J. et al International Archives of Allergy and Immunology 2006, 141:119 –129
IgE-Mediated Allergen Presentation and Blocking Antibodies: Regulation of T-Cell Activation in Allergy.
Hegmans, J.P.J.J., Boon, L. et al European Respiratory Journal 2006, 27: 1086–1095
Mesothelioma environment comprises cytokines and T-regulatory cells that suppress immune responses.
Coenen, J.J.A., Boon, L. et al Journal of Immunology 2006, 176: 5240-5246
CTLA-4 Engagement and Regulatory CD4+CD25+ T Cells Independently Control CD8-Mediated Responses under Costimulation Blockade.
Jeurissen, A., Boon, L. et al Journal of Immunology 2006, 176: 529-536
CD4+ T Lymphocytes Expressing CD40 Ligand Help the IgM Antibody Response to Soluble Pneumococcal Polysaccharides via an Intermediate Cell Type.
Nierkens, S., Boon, L. et al Journal of Immunotoxicology 2005, 2: 141-150
Drug-Induced Type 1 and Type 2 Immune Responses are Characterized by Distinct Profiles of Cell Kinetics, Cytokine Production, and Expression of Co-Stimulatory Molecules in the Popliteal Lymph Node Assay.
Boudewijns, M., Boon, L. et al Journal of Leukocyte Biology 2005, 78: 1060-1069
Blockade of CTLA-4 (CD152) enhances the murine antibody response to pneumococcal capsular polysaccharides.
Simons, P.J., Boon, L. et al Cytokine 2005, 32: 94-103
Cytokine-mediated modulation of leptin and adiponectin secretion during in vitro adipogenesis: Evidence that TNF-α and IL-1β- treated human preadipocytes are potent leptin producers.
Nierkens, S., Boon, L. et al Journal of Immunology 2005, 175: 3707-3714
Differential requirement for CD28/CTLA-4 - CD80/CD86 interactions in drug-induced Type 1 and type 2 immune responses to Trinitrophenyl-Ovalbumin.
Wijk, F. van, Boon, L. et al Journal of Immunology 2005, 174: 174-179
CTLA-4 signaling regulates the intensity of a food allergic response, but is not decisive in the induction of sensitization to food antigens.
Rayman, N., Simons, P.J. et al Journal of Immunology 2004, 172: 2111-2117
Distinct Expression profiles of the peripheral cannabinoid receptor in lymphoid tissue depending on receptor activation status.
Koenen, H.J.P.M., Simons, P.J., Hartog, M.T. den & Boon, L. et al Transplantation 2004, 78: 1429-1438
A novel bi-specific anti-human CD40/CD86 fusion protein with T-cell tolerizing potential.
