Bioceros offers the following services to customers:

• Generation and selection of novel functional active therapeutic monoclonal antibodies.
   
• Development of accompanying cellular assays for functional characterization.
   
• Generation of CHO- or PER.C6^®-based cell lines that produce high level recombinant proteins or monoclonal antibodies.
  • Note: for generation of the cell lines, either standard plasmid vectors (available at Bioceros) or Crucells STAR^®-Select technology may be used. Bioceros is allowed to out-license STAR^®-Select from Crucell.
  • Note: PER.C6^® services can only be provided to customers who have obtained a PER.C6^® license from Crucell/DSM.
  • Note: Potelligent^® services can only be provided to customers who have obtained a Potelligent^® license from BioWa.

• Manufacturing of recombinant proteins up to 20L scale.
   
• Development and execution of cell-based assays for development (potency, release testing and immunogenicity).
   
• Consultancy services for immunohistochemistry and in vivo PoC and toxicity studies (rodents, nonhuman primates).

 

Click the above image to view the full-size version.